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Till Strowig

Braunschweig/DE

Current Position and Affiliations: Head of Department “Microbial Immune Regulation” at the Helmholtz Centre for Infection Research & W3-Professorship at the Hannover Medical School [since 2019]
Recent Research Topics  
  • Microbiome Research
  • MDR-Enterobacterales
 
Previous Positions  
  • Head of Young Investigator Research group at the Helmholtz Centre for Infection Research [2013-2019]
  • Postdoc in Department of Immunobiology at Yale University, New Haven, USA (Advisor Richard Flavell) [2009-2013]
 
Scientific Degrees  
  • PhD in Viral Immunobiology, The Rockefeller University, New York, USA, Mentor: Prof. Christian Münz [2009]
  • Dipl.Ing. in Medical Biotechnology, Technische Universität Berlin, Berlin, Germany [2004]
 
Current Funding (sorted by starting date)  
  • DFG EXC RESIST: Co-PI in two subprojects of EXC (Projekt B1, Projekt B2) [2019-2025]
  • ERC CoG: Partner w/ S. Huber (UKE Hamburg) topic: Role of microbiota in regulation of IL-22/IL-22bp axis [2020-2026]
  • DZIF: PI (Einzelvorhaben, Enhance Decolonize) [2021-2026]
  • DFG (Einzelantrag, PrevoRA) [2022-2025]
  • BMBF: co-PI (TAhRget) [2022-2025]
  • DFG (SeqCall, OrganCrossTalk NAKO) [2023-2026]
  • DZIF: co-PI (DZG Microbiome Call) [2023-2026]
  • Volkswagen Stiftung (Nds-Israel Project) [2023-2026]
  • DZIF: co-PI (FlexFunds EVREA-Phage)[2024-2025]
  • DZIF: co-PI (RESET-MDR) [2024-2028]
  • DZIF: PI (Einzelvorhaben, RD-MICOs) [2024-2025]
  • EMBL: co-PI (Amplifying Grants in Infection Biology) [2025-2027]
  • Helmholtz Enterprise Spin-off Project: PI (DeKox) [2025-2026]
  • HZI-IVF: PI Prevention [2025]
 
Publications  
  1. Almási ÉDH, Eisenhard L*, Osbelt L*, Lesker TR, Vetter AC, Knischewski N, Bielecka AA, Gronow A, Muthukumarasamy U, Wende M, Tawk C, Neumann-Schaal M, Brönstrup M, Strowig T (2025). “Klebsiella oxytoca facilitates microbiome recovery via antibiotic degradation and restores colonization resistance in a diet-dependent manner.” Nature Communications 16(1): 551.
  2. El Mouali Y, Tawk C, Huang KD, Amend L, Lesker TR, Ponath F, Vogel J, Strowig T (2024). “The RNA landscape of the human commensal Segatella copri reveals a small RNA essential for gut colonization.” Cell Host & Microbe 32(11): 1910-1926.e6.
  3. Osbelt L, Almási E, Wende M, Kienesberger S, … , Flieger A, Schlüter D, Müller R, Erhardt M, Zechner EL, Strowig T (2024). “Klebsiella oxytoca inhibits Salmonella infection through multiple microbiota-context-dependent mechanisms.” Nature Microbiology 9(7): 1792-1811.
  4. Huang KD, Amend L, Gálvez EJC, Lesker TR, …, Segata N, Esser S, Strowig T, Kehrmann J (2024). “Establishment of a non-Westernized gut microbiota in men who have sex with men is associated with sexual practices.” Cell Reports Medicine 5(3): 101426.
  5. Blanco-Míguez A, Gálvez EJC, Pasolli E, … , Ercolini D, Segata N, Strowig T (2023). “Extension of the Segatella copri complex to 13 species with distinct large extrachromosomal elements and associations with host conditions.” Cell Host & Microbe 31(11): 1804-1819e9.
  6. Osbelt L, Wende M, Almási E, Derksen E, …, Neumann-Schaal M, Fischer T, Schlüter D, Strowig T (2021). „Klebsiella oxytoca causes colonization resistance against multidrug-resistant Klebsiella pneumoniae in the gut via cooperative carbohydrate competition.” Cell Host & Microbe 29(11): 1663-1679.
  7. Gálvez EJC, Iljazovic A, Amend L, Lesker TR, Renault T, Thiemann S, Hao L, Roy U, Gronow A, Charpentier E, Strowig, T (2020). “Distinct polysaccharide utilization as determinants for interspecies competition between intestinal Prevotella spp.” Cell Host & Microbe 28(6): 838-852
  8. Iljazovic A, Roy U, Gálvez EJC, Lesker TR, …, Neumann-Schaal M, Strowig, T (2020). “Perturbation of the gut microbiome by Prevotella spp. enhances host susceptibility to mucosal inflammation.” Mucosal Immunology 14: 113–124.
  9. Elinav E*, Strowig T*, Kau AL, Henao-Mejia J, Thaiss CA, Booth CJ, Peaper DR, Bertin J, Eisenbarth SC, Gordon JI, Flavell RA (2011). “NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis.” Cell 145(5): 745-57.
*: shared authorship
Patents and Transfer activities  
  • Patent Application: Decolonization of Enterobacteria, such as Klebsiella pneumoniae, from the gut using strains of Klebsiella oxytoca (EP21 823 909.3 and US 18/266,327)
  • Patent Application: Decolonization of pathogenic enterobacteria, such as E. coli and/or Klebsiella pneumoniae, from the gut using strains of E. coli (EP24182102.4)
 
Activities in the Research System  
  • Member Steering Committee EXC RESIST (since 2019)
  • Member of the steering committee, DZIF Academy (since 2019)
  • Spokesperson DGHM FG “Microbiota and Host” (since 2024)
  • Spokesperson of the DZIF Bridging Topics „Microbiome“ (since 2022)
  • Reviewer: Deutsche Forschungsgemeinschaft (DFG), Swiss National Science Foundation (SNSF), French National Science Foundation (ANR)
  • Editorial board: Microbiome
  • Reviewer Journals: Nat Microbiol., Cell Host Microbe, Cell Reports, Microbiome, Science Transl Med., PLoS Pathog., J Immunol., etc.
  • Memberships: German Society of Hygiene and Microbiology (DGHM), German Society of Immunology (DGfI)